Here is some exciting news via a Tweet from Asus. They plan to release the unlock tool they have hinted at for the Transformer Prime very soon. In fact, they indicated in would be out sometime in February. Interestingly, the first Tweet to share the info accidentally said, "root tool", but later they sent out an updated Tweet that corrected that to mean "unlock tool." You can see them both above and below. This is awesome news for us tinkerers!
Source: TransformerForums.com via TalkAndroid