Picked mine up Wednesday (9-15). Really, really nice phone. It's a lot faster/smoother than my overclocked D1.

Out of the box has Sense UI running on top of 2.1. Unlike what I've read about other Desires, this one does not have Flash. Cellular South has added a few of their own 'bloatware' apps (a music player, customer service, their own app store). To their credit, the have not physically badged the phone in any way. They also seem to have allowed tethering (for now).